Quantification and comparison of the neuroarchitecture of deep cerebellar nuclei in the rat and macaque

DSpace Repository

Show simple item record

dc.contributor.advisor Sultan, Fahad (Prof. Dr.)
dc.contributor.author Mao, Haian
dc.date.accessioned 2019-12-09T08:31:09Z
dc.date.available 2019-12-09T08:31:09Z
dc.date.issued 2019-12-09
dc.identifier.other 1684871654 de_DE
dc.identifier.uri http://hdl.handle.net/10900/95589
dc.identifier.uri http://nbn-resolving.de/urn:nbn:de:bsz:21-dspace-955895 de_DE
dc.identifier.uri http://dx.doi.org/10.15496/publikation-36972
dc.description.abstract The human cerebellum contains 70% of all neurons in the brain and has expanded considerably in the course of primate and mammalian evolution. This expansion is due to the emergence of the neocerebellum consisting of the cerebellar hemispheres and its output structure, the dentate nucleus. Its function, however, remains something of an enigma to cognitive neuroscience and psychology. The aim of this dissertation is to further our understanding of the processes behind cerebellar evolution by studying the cellular changes in the dentate that led to the specialized human neocerebellum. Our results show that the hypo-scaling of dentate dendrites and excitatory synaptic number would aid and abet a larger number of cerebellar modules in hominoids and humans and could be interpreted as a special miniaturization of the computational units in primate neocerebellum. Our findings shed new light on the special neuroarchitecture of the dentate nucleus and provide a new working hypothesis for the unusual folded and flattened nature of the dentate. en
dc.language.iso en de_DE
dc.publisher Universität Tübingen de_DE
dc.rights ubt-podok de_DE
dc.rights.uri http://tobias-lib.uni-tuebingen.de/doku/lic_mit_pod.php?la=de de_DE
dc.rights.uri http://tobias-lib.uni-tuebingen.de/doku/lic_mit_pod.php?la=en en
dc.subject.classification Kleinhirn , Evolution , Vergleichende Anatomie , Immunohistologie , Morphologie de_DE
dc.subject.ddc 500 de_DE
dc.subject.ddc 570 de_DE
dc.subject.other Deep cerebellar nuclei en
dc.subject.other dentate nucleus en
dc.subject.other macaque en
dc.subject.other vGluT en
dc.subject.other excitatory synapse en
dc.subject.other dendrite en
dc.title Quantification and comparison of the neuroarchitecture of deep cerebellar nuclei in the rat and macaque en
dc.type PhDThesis de_DE
dcterms.dateAccepted 2019-11-26
utue.publikation.fachbereich Biologie de_DE
utue.publikation.fakultaet 7 Mathematisch-Naturwissenschaftliche Fakultät de_DE


This item appears in the following Collection(s)

Show simple item record