PMNs, naRNA-LL37 complexes and platelets - a vicious inflammatory 'trio' in psoriasis

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PMNs, naRNA-LL37 complexes and platelets - a vicious inflammatory 'trio' in psoriasis

Herster, Franziska
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URI: http://hdl.handle.net/10900/90969
http://nbn-resolving.de/urn:nbn:de:bsz:21-dspace-909695
http://dx.doi.org/10.15496/publikation-32350
Dokumentart: PhDThesis
Date: 2020-06-30
Language: English
Faculty: 7 Mathematisch-Naturwissenschaftliche Fakultät
Department: Biologie
Advisor: Weber, Alexander N.R. (Prof. PhD)
Day of Oral Examination: 2019-07-15
DDC Classifikation: 500 - Natural sciences and mathematics
570 - Life sciences; biology
610 - Medicine and health
Other Keywords:
Psoriasis
PMNs
platelets
License: http://tobias-lib.uni-tuebingen.de/doku/lic_ohne_pod.php?la=de http://tobias-lib.uni-tuebingen.de/doku/lic_ohne_pod.php?la=en
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Abstract:

Psoriasis is an autoinflammatory skin disease with high incidence (3% of adults) in Western countries, accompanied by personal and socioeconomic burden. Psoriatic skin lesions are characterized by hyperproliferating keratinocytes, by vasodilatation in the dermis and most importantly by skin infiltration of leukocytes, dominated by neutrophils (PMNs).

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