Reclassification of ATM Missense Variants of Uncertain Significance by Integrating Results from Systematic Functional Assays into an ACMG Points-Based Framework

Hanenberg, Helmut; Zhang, Fan; Malev, Nikita; Wiek, Constanze; Klamer, Brett G.; Nassar, Nicolas; Hesselbrock, Tyler; Hanenberg, Judith H.; Aeilts, Amber M.; Hentschel, Julia; Faust, Ulrike; Gehrig, Andrea; Engel, Christoph; Hauke, Jan; Niederacher, Dieter; Toland, Amanda E.; Andreassen, Paul R.

Reclassification of ATM Missense Variants of Uncertain Significance by Integrating Results from Systematic Functional Assays into an ACMG Points-Based Framework

Autor(en):

Hanenberg, Helmut; Zhang, Fan; Malev, Nikita; Wiek, Constanze; Klamer, Brett G.; Nassar, Nicolas; Hesselbrock, Tyler; Hanenberg, Judith H.; Aeilts, Amber M.; Hentschel, Julia; Faust, Ulrike; Gehrig, Andrea; Engel, Christoph; Hauke, Jan; Niederacher, Dieter; Toland, Amanda E.; Andreassen, Paul R.

Tübinger Autor(en):

Faust, Ulrike E. A.

Erschienen in:

Clinical Cancer Research (2025), Bd. 31, H. 12, S. 2426-2440

Verlagsangabe:

Philadelphia : Amer Assoc Cancer Research

Sprache:

Englisch

Referenz zum Volltext:

http://dx.doi.org/10.1158/1078-0432.CCR-24-3936

ISSN:

1078-0432