BRAFΔß3-αC in-frame deletion mutants differ in their dimerization propensity, HSP90 dependence, and druggability

Lauinger, Manuel; Christen, Daniel; Klar, Rhena F. U.; Roubaty, Carole; Heilig, Christoph E.; Stumpe, Michael; Knox, Jennifer J.; Radulovich, Nikolina; Tamblyn, Laura; Xie, Irene Y.; Horak, Peter; Forschner, Andrea; Bitzer, Michael; Wittel, Uwe A.; Boerries, Melanie; Ball, Claudia R.; Heining, Christoph; Glimm, Hanno; Froehlich, Martina; Huebschmann, Daniel; Gallinger, Steven; Fritsch, Ralph; Froehling, Stefan; O'Kane, Grainne M.; Dengjel, Joern; Brummer, Tilman

BRAFΔß3-αC in-frame deletion mutants differ in their dimerization propensity, HSP90 dependence, and druggability

Author:

Lauinger, Manuel; Christen, Daniel; Klar, Rhena F. U.; Roubaty, Carole; Heilig, Christoph E.; Stumpe, Michael; Knox, Jennifer J.; Radulovich, Nikolina; Tamblyn, Laura; Xie, Irene Y.; Horak, Peter; Forschner, Andrea; Bitzer, Michael; Wittel, Uwe A.; Boerries, Melanie; Ball, Claudia R.; Heining, Christoph; Glimm, Hanno; Froehlich, Martina; Huebschmann, Daniel; Gallinger, Steven; Fritsch, Ralph; Froehling, Stefan; O'Kane, Grainne M.; Dengjel, Joern; Brummer, Tilman

Tübinger Autor(en):

Bitzer, Michael
Forschner, Andrea Lydia

Published in:

Science Advances (2023), Bd. 9 (35), Article eade7486

Verlagsangabe:

Washington : Amer Assoc Advancement Science

Language:

English

Full text:

http://dx.doi.org/10.1126/sciadv.ade7486

ISSN:

2375-2548