Browsing Universitätsbibliographie by Author "Kahle, Philipp J."

Now showing items 21-40 of 47

LRRK2 functions as a scaffolding kinase of ASK1-mediated neuronal cell death

Yoon, Ji-Hye; Mo, Jung-Soon; Kim, Mi-Yeon; Ann, Eun-Jung; Ahn, Ji-Seon; Jo, Eun-Hye; Lee, Hye-Jin; Lee, Young Chul; Seol, Wongi; Yarmoluk, Sergiy M.; Gasser, Thomas; Kahle, Philipp J.; Liu, Guang-Hui; Belmonte, Juan Carlos Izpisua; Park, Hee-Sae (2017)
Mapping of Surface-Exposed Epitopes of In Vitro and In Vivo Aggregated Species of Alpha-Synuclein

Almandoz-Gil, Leire; Lindstrom, Veronica; Sigvardson, Jessica; Kahle, Philipp J.; Lannfelt, Lars; Ingelsson, Martin; Bergstrom, Joakim (2017)
Medin aggregation causes cerebrovascular dysfunction in aging wild-type mice

Degenhardt, Karoline; Wagner, Jessica; Skodras, Angelos; Candlish, Michael; Koppelmann, Anna Julia; Wild, Katleen; Maxwell, Rusheka; Rotermund, Carola; von Zweydorf, Felix; Gloeckner, Christian Johannes; Davies, Hannah A.; Madine, Jillian; Del Turco, Domenico; Feederle, Regina; Lashley, Tammaryn; Deller, Thomas; Kahle, Philipp; Hefendehl, Jasmin K.; Jucker, Mathias; Neher, Jonas J. (2020)
Metformin lowers Ser-129 phosphorylated alpha-synuclein levels via mTOR-dependent protein phosphatase 2A activation

Perez-Revuelta, B. I.; Hettich, M. M.; Ciociaro, A.; Rotermund, C.; Kahle, P. J.; Krauss, S.; Di Monte, D. A. (2014)
Microglial inclusions and neurofilament light chain release follow neuronal alpha-synuclein lesions in long-term brain slice cultures

Barth, Melanie; Bacioglu, Mehtap; Schwarz, Niklas; Novotny, Renata; Brandes, Janine; Welzer, Marc; Mazzitelli, Sonia; Haesler, Lisa M.; Schweighauser, Manuel; Wuttke, Thomas, V; Kronenberg-Versteeg, Deborah; Fog, Karina; Ambjorn, Malene; Alik, Ania; Melki, Ronald; Kahle, Philipp J.; Shimshek, Derya R.; Koch, Henner; Jucker, Mathias; Tanrioever, Gaye (2021)
Monitoring -synuclein multimerization in vivo

Prasad, Vibha; Wasser, Yasmine; Hans, Friederike; Goswami, Anand; Katona, Istvan; Outeiro, Tiago F.; Kahle, Philipp J.; Schulz, Joerg B.; Voigt, Aaron (2019)
Monoclonal antibodies selective for alpha-synuclein oligomers/protofibrils recognize brain pathology in Lewy body disorders and alpha-synuclein transgenic mice with the disease-causing A30P mutation

Fagerqvist, Therese; Lindstrom, Veronica; Nordstrom, Eva; Lord, Anna; Tucker, Stina M. E.; Su, Xingjian; Sahlin, Charlotte; Kasrayan, Alex; Andersson, Jessica; Welander, Hedvig; Nasstrom, Thomas; Holmquist, Mats; Schell, Heinrich; Kahle, Philipp J.; Kalimo, Hannu; Moller, Christer; Gellerfors, Par; Lannfelt, Lars; Bergstrom, Joakim; Ingelsson, Martin (2013)
Multiple distinct pathways lead to hyperubiquitylated insoluble TDP-43 protein independent of its translocation into stress granules

Hans, Friederike; Glasebach, Hanna; Kahle, Philipp J. (2020)
Neurofilament light chain in blood and CSF as marker of disease progression in mouse models and in neurodegenerative diseases

Bacioglu, Mehtap; Maia, Luis F.; Preische, Oliver; Schelle, Juliane; Apel, Anja; Kaeser, Stephan A.; Schweighauser, Manuel; Eninger, Timo; Lambert, Marius; Pilotto, Andrea; Shimshek, Derya R.; Neumann, Ulf; Kahle, Philipp J.; Staufenbiel, Matthias; Neumann, Manuela; Maetzler, Walter; Kuhle, Jens; Jucker, Mathias (2016)
Nuclear import factor transportin and arginine methyltransferase 1 modify FUS neurotoxicity in Drosophila

Jaeckel, Sandra; Summerer, Anna K.; Thoemmes, Catherine M.; Pan, Xia; Voigt, Aaron; Schulz, Joerg B.; Rasse, Tobias M.; Dormann, Dorothee; Haass, Christian; Kahle, Philipp J. (2015)
Off-pathway alpha-synuclein oligomers seem to alter alpha-synuclein turnover in a cell model but lack seeding capability in vivo

Fagerqvist, Therese; Nasstrom, Thomas; Ihse, Elisabet; Lindstrom, Veronica; Sahlin, Charlotte; Tucker, Stina M. Fangmark; Kasaryan, Alex; Karlsson, Mikael; Nikolajeff, Fredrik; Schell, Heinrich; Outeiro, Tiago F.; Kahle, Philipp J.; Lannfelt, Lars; Ingelsson, Martin; Bergstrom, Joakim (2013)
Overexpression of synphilin-1 promotes clearance of soluble and misfolded alpha-synuclein without restoring the motor phenotype in aged A30P transgenic mice

Casadei, Nicolas; Poehler, Anne-Maria; Tomas-Zapico, Cristina; Torres-Peraza, Jesus; Schwedhelm, Ivo; Witz, Annemarie; Zamolo, Irina; De Heer, Raymond; Spruijt, Berry; Noldus, Lucas P. J. J.; Klucken, Jochen; Lucas, Jose J.; Kahle, Philipp J.; Krueger, Rejko; Riess, Olaf; Nuber, Silke (2014)
Overexpression of the calpain-specific inhibitor calpastatin reduces human alpha-Synuclein processing, aggregation and synaptic impairment in [A30P]alpha Syn transgenic mice

Diepenbroek, Meike; Casadei, Nicolas; Esmer, Hakan; Saido, Takaomi C.; Takano, Jiro; Kahle, Philipp J.; Nixon, Ralph A.; Rao, Mala V.; Melki, Ronald; Pieri, Laura; Helling, Stefan; Marcus, Katrin; Krueger, Rejko; Masliah, Eliezer; Riess, Olaf; Nuber, Silke (2014)
Parkinson's disease: dopaminergic nerve cell model is consistent with experimental finding of increased extracellular transport of alpha-synuclein

Buechel, Finja; Saliger, Sandra; Draeger, Andreas; Hoffmann, Stephanie; Wrzodek, Clemens; Zell, Andreas; Kahle, Philipp J. (2013)
Prominent microglial inclusions in transgenic mouse models of alpha-synucleinopathy that are distinct from neuronal lesions

Tanrioever, Gaye; Bacioglu, Mehtap; Schweighauser, Manuel; Mahler, Jasmin; Wegenast-Braun, Bettina M.; Skodras, Angelos; Obermueller, Ulrike; Barth, Melanie; Kronenberg-Versteeg, Deborah; Nilsson, K. Peter R.; Shimshek, Derya R.; Kahle, Philipp J.; Eisele, Yvonne S.; Jucker, Mathias (2020)
Regulation of mitochondrial cargo-selective autophagy by posttranslational modifications

Terradas, Anna Lechado; Zittlau, Katharina, I; Macek, Boris; Fraiberg, Milana; Elazar, Zvulun; Kahle, Philipp J. (2021)
Regulatory effects of SKAR in interferon alpha signaling and its role in the generation of type I IFN responses

Kroczynska, Barbara; Mehrotra, Swarna; Majchrzak-Kita, Beata; Arslan, Ahmet Dirim; Altman, Jessica K.; Stein, Brady L.; McMahon, Brandon; Kozlowski, Piotr; Kahle, Philipp J.; Eklund, Elizabeth A.; Fish, Eleanor N.; Platanias, Leonidas C. (2014)
Signatures of glial activity can be detected in the CSF proteome

Eninger, Timo; Mueller, Stephan A.; Bacioglu, Mehtap; Schweighauser, Manuel; Lambert, Marius; Maia, Luis F.; Neher, Jonas J.; Hornfeck, Sarah M.; Obermueller, Ulrike; Kleinberger, Gernot; Haass, Christian; Kahle, Philipp J.; Staufenbiel, Matthias; Ping, Lingyan; Duong, Duc M.; Levey, Allan, I; Seyfried, Nicholas T.; Lichtenthaler, Stefan F.; Jucker, Mathias; Kaeser, Stephan A. (2022)
Sirtuin-1 sensitive lysine-136 acetylation drives phase separation and pathological aggregation of TDP-43

Morato, Jorge Garcia; Hans, Friederike; von Zweydorf, Felix; Feederle, Regina; Elsasser, Simon J.; Skodras, Angelos A.; Gloeckner, Christian Johannes; Buratti, Emanuele; Neumann, Manuela; Kahle, Philipp J. (2022)
TDP-43 regulates global translational yield by splicing of exon junction complex component SKAR

Fiesel, Fabienne C.; Weber, Stephanie S.; Supper, Jochen; Zell, Andreas; Kahle, Philipp J. (2012)

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