The immunoreceptor NKG2D promotes immunosurveillance of malignant cells and protects the host from tumour initiation by activating NK cells and costimulating CD8 T cells. MICA and other ligands of NKG2D are frequently ...
African trypanosomiasis is caused by extra cellular parasitic protozoa that can be transmitted by the bite of a tsetse fly. The disease is caused by sub-species of Trypanosoma brucei, an extra-cellular eukaryotic flagellated ...
Dendritic cells are integral components of the mammalian immune system, which take part in orchestrating and regulating the delicate balance of immune response. Dendritic cells are potent activators of destructive responses ...